Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab

Erik van Dijk, Hedde D. » read more


Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer

Zuurbier L et al Oncotarget. 2017 Jun 27;8(26):42949-42961. doi: 10.18632/oncotarget.17306. » read more


Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach

Moran B et al Oncotarget. 2017 Jul 18;8(29):48126-48137. doi: 10.18632/oncotarget.18296. » read more


PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Meehan et al Cancer Res. 2017 Nov 1;77(21):e62-e66. doi: 10.1158/0008-5472.CAN-17-0582 » read more


A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate

O'Farrell and Evans et al PLoS One. 2017 Jan 27;12(1):e0169964. doi: 10.1371/journal.pone.0169964. eCollection 2017 » read more


Interrogating open issues in cancer precision medicine using Patient-Derived Xenograft Models

Byrne AT et al. Nat Rev Cancer. 2017 Apr;17(4):254-268. doi: 10.1038/nrc.2016.140. Epub 2017 Jan 20 » read more


Outcome of colorectal cancer patients treated with combination Bevacizumab therapy: A pooled retrospective analysis of four European cohorts from the ANGIOPREDICT initiative.

Betge J, Barat A, Murphy V, Hielscher T, Van Grieken NC, Belle S, Zhan T, Härtel N, Kripp M, Bacon O, Cordes M, Kay EW, Verheul HMW, Neerincx M, Hennessy B, Hofheinz RD, Gaiser T, Ylstra B, Prehn JHM, Lambrechts D, Byrne AT, Ebert MP, Schulte N Digestion. 2016;94(3):129-137. doi: 10.1159/000449412. PMID: 27756074 » read more


AKT1 (E17K) Mutation Profiling in Breast Cancer: Prevalence, Concurrent Oncogenic Alterations, and Blood-based Detection

M Rudolph, T Anzeneder, A Schulz, G Beckmann, AT Byrne, M Jeffers, C Pena, O Politz, K Köchert, R Vonk, J Reischl BMC Cancer. 2016 Aug 11;16:622. doi: 10.1186/s12885-016-2626-1. PMID: 27515171 » read more


The IL-17-Th1/Th17 pathway: An attractive target for lung cancer therapy?

M Joerger, SP Finn, S Cuffe, AT Byrne & SG Gray Expert Opin Ther Targets. 2016 Jul 11:1-18. [Epub ahead of print] PMID: 27353429 » read more


Modelling tumour cell proliferation from vascular structure using tissue decomposition into avascular elements

Besenhard MO, Jarzabek M, O'Farrell AC, Callanan JJ, Prehn JH, Byrne AT, Huber HJ J Theor Biol. 2016 Aug 7;402:129-43. PMID: 27155046. » read more